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Specifically activate targets and target subpopulations to increase efficacy and reduce intolerable side effects
Activate hypertrophy to combat muscle loss during weight loss.
Activate hypertrophy to combat muscle loss during weight loss.
Metabolic
Inflammation
Activate wound-healing to address disease causes, not just treat symptoms
Allosterically activate hydrophobic ligand responsive receptors from the outside of the cell, sidestepping problems of hydrophobic drugs that bind orthosterically.
Allosterically activate hydrophobic ligand responsive receptors from the outside of the cell, sidestepping problems of hydrophobic drugs that bind orthosterically.
Cancer
Locally recruit and activate tumor-killing T cells to tumors with chemokine receptor activators
Activate receptor internalization to expand the therapeutic windows of ADCs.
Activate receptor internalization to expand the therapeutic windows of ADCs.
